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2) Improved Cognition As has previously been stated, NAD+ has been shown to exert both protective and stimulatory effects on the brain

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Biochemical Journal, 1965, 94(3): 705

Weeks 516: 200 mcg once daily for maximal effect in most research scenarios

The activity of the proteasome is significantly decreased in the hippocampus, middle temporal gyri, and inferior temporal lobe of AD subjects (331, 348, 349)