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Therefore, this narrative review navigates into the intricate role of TRP metabolism in insomnia and its psychological and neurological comorbidities, particularly cognitive dysfunction, depression, anxiety, stress, traumatic brain injury (TBI), chronic pain, and substance abuse

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An interesting study demonstrated that Nrf2 has detrimental effects on the heart by promoting ferroptosis during myocardial autophagy deficiency (100)

Stimulates and maintains appetite

[DOI] [Google Scholar] 48.Beitzke B., Pate D.W

doi: 10.3390/ijms20246257 14 CapuozzoMSantorsolaMBocchettiMPerriFCascellaMGranataVet al