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Lactate production is a prioritized feature of adipocyte metabolism

The homogenate was centrifuged at 10,000 rpm for 20 min and clear supernatants were collected and stored on ice until the time of the assay

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A study on metabolically healthy men found that 12-week synbiotic intervention significantly reduced serum alanine aminotransferase levels, with a 20.70% reduction in the subgroup with elevated body fat percentage, and significant changes in gut microbiome composition occurred in this subgroup, suggesting synbiotics may exert hepatoprotective effects on specific populations by regulating gut flora

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10.3389/fphar.2023.1231450 131