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While this specific trial was limited by a small sample size and high dropout rates (which impacted the statistical significance between the placebo and active groups), larger ongoing trials, such as a 310-patient study (NCT05703074), are currently underway to rigorously test NR's ability to combat physical and cognitive fatigue

Inflammation, high density lipoprotein and endothelium

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Trypsin activity was stopped by adding 10% fetal serum, before centrifuging the tissue at 700 g for 5 min in a microfuge at 4 C