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As it is not naturally present in fruit, vegetables, and grains, vegans may not get sufficient amounts of vitamin B12 in their diet

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Because they work upstream of growth hormone, the body's own feedback systems remain active, and supraphysiologic levels cannot be produced

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Note that ATP is not included in this list, given that a catalytically inactive pyruvate kinase (such as dimeric PKM2) would greatly diminish the net ATP output of glycolysis, see the energetics of cancer glycolysis in ref