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In monotherapy, thioctic acid was most used, followed by anti-convulsive agents, tricyclic antidepressant (TCA)

Lauridsen, M

10.1016/j.tem.2016.11.002 Trends Endocrinol Metab

Possible clues include fatigue, exercise intolerance, cognitive variability, poor recovery after infection, worsening with fasting, muscle weakness or regression during metabolic stress