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Notably, the Cu ion carrier-induced cell death pathway cannot be treated with inhibitors of other known cell death pathways, such as pan-cysteine aspartase inhibitors (anti-apoptotic compounds), Fe inhibitor-1 (an anti-Fe apoptotic compound), necrosin-1 (an anti-apoptotic compound), and N-acetylcysteine (an oxidative stress inhibitor), suggesting that cuproptosis mechanisms are distinct from previously identified cell death pathways, e.g

Role of STAT3 signaling pathway in breast cancer

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In order to maintain an appropriate number of mitochondria in sperm, the replication and subcellular organization of mitochondrial DNA must be accurately controlled during spermatogenesis, otherwise it may cause asthenospermia