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However, when serine is available, neither restricting exogenous glycine intake nor depleting the endogenous glycine cleavage system can inhibit the proliferation of cancer cells, indicating that nucleotide synthesis and cancer cell growth are supported by serine rather than glycine consumption [171]

Ph liu

Endothelial sensing of AHR ligands regulates intestinal homeostasis

Cell 21 , 835847 (2011)

For values in the so-called gray area between 35 and 50, the determination of homocysteine and methylmalonic acid may be helpful to confirm a deficiency