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Breau, M

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Additionally, remodeling of the ECM in TDLNs is also thought to occur as part of the pre-metastatic niche formation, but the mechanisms that underlie this process and their molecular players remain to be uncovered ( A single-cell analysis carried out in cells isolated from murine breast cancer models showed changes in immune modulation and metabolism in TDLNs (174)

It was shown by them that d-tocotrienol augmented gemcitabine activity in vitro and in vivo

These results supported that compound 102 was a specific GPX4 activator, and increasing GPX4 activity would be an alternative way to suppress ferroptosis

Biochem J 410:525534 Hong SH, Lee D-H, Lee Y-S et al (2017) Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER stress-induced p53-independent PUMA expression