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Description

Biguanide-derived neuroprotective agent (metformin) To mitigate neuroinflammation and mitochondrial dysfunction in PD, metformin was encapsulated into PLGA, which were further coated with BV2 microglial cell membranes to enhance the targeting efficiency to neuroinflammatory sites (BV2-metformin-loaded PLGA) for intranasal administration 19

Compend Contin Educ Vet (2012) 34:E14

Note: This comparison is limited by differences between studies with respect to the quality of the studies, the patient populations studied, the severity of the underlying condition, generally DPN