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Step 4: Relax during session Most patients simply relax during the treatment

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PLoS ONE 8(9):e75604

A systematic review of randomized controlled trials

First described back in the 1950s, acne erupts in about one in ten people within days or even hours of getting an injection of vitamin B12, which then disappears rapidly when injection treatment is discontinued. At the time, we had no idea what the mechanism might be, and the problem remained unsolved until just a few years ago when we finally figured it out: Vitamin B12 modulates the gene expression of the skin bacteria that cause acne

The extended half-life eliminates the need to use reagent injectors and provides flexibility for continuous or batch mode processing of multiple plates