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However, its role in boosting glutathione levels is complex, as this process depends on the availability of other amino acids (glycine and glutamate) and enzymatic efficiency

SLC25A39 as well as mitochondrial GSH may also represent promising drug targets for cancer, since manipulating SLC25A39 functioning or mitochondrial GSH in tumor cells may induce selective oxidative stress, leading to cell death

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Plant Cell 20 , 786802 (2008)

We hypothesized that the activation of the NGF/TrkA signaling pathway in the striatum after BSO, might be associated with the transcriptional upregulation of the amino acid transporters genes related to the availability of L-cys and L-cys 2