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Microbial changes and host response in F344 rat colon depending on sex and age following a high-fat diet (in Eng)

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The agency cited safety risks including potential carcinogenicity, immunogenicity, and concerns about impurities and noted that most of these substances had never undergone rigorous human clinical trials

Animal toxicity studies found no lethal dose for BPC-157, an unusual characteristic suggesting a wide safety margin

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May stimulate proteoglycan synthesis though direct cartilage regeneration evidence limited