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However, when uric acid concentrations exceed normal levels, it exhibits pro-oxidant effects, increasing the production of reactive oxygen species (ROS)

Acute Med

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Although astrocytes can utilize fatty acids as an alternative energy source, prolonged reliance on lipid oxidation results in oxidative stress and mitochondrial impairment, exacerbating neurodegeneration 82

Here, living bacteria are found to be surprisingly tolerant towards changes in membrane fluidity, thus questioning the dogma that careful regulation of membrane fluidity is critical for supporting general activities of membraneassociated processes