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Pharmacokinetics and Metabolism of Natural Methylxanthines in Animal and Man

This is more common in the case of cysteine and glutamine and less common in the case of glycine

For instance, methylation is nonexistent in Brachionus koreanus [73, 74] and moderately abundant (roughly 30% of CpG dinucleotides) in Hydra vulgaris [75], suggesting that there is no universal functional role for DNA methylation across all invertebrates