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Tumor cell mutation: Most human tumors are not driven by active virus infection, but malignant cells are often accompanied by an increase in gene mutation rate during immune escape (92, 93)

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Stem cell replenishment of the trabecular meshwork system in experimental glaucoma models has also been shown to act on underlying disease pathologies, with studies demonstrating improvements in IOP levels, aqueous humor outflow, trabecular meshwork cellularity, and RGC neuroprotection (Zhu et al., 2016

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