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MYC indirectly regulates GLS via suppression of specific miRNAs 14

Sadly, patients are often affected for 7-10 years before finally receiving a diagnosis, leading to devastating and poor quality of life

10.1016/j.neuro.2022.03.005 117 ZhouY.ZhengJ.LiY.XuD

Recent studies have shown that dietary Aspergillus oryzae -derived protease markedly increases the abundance of both Bifidobacterium and Lactobacillus in the rat cecum and induces the production of various postbiotics, including GABA, which was not detected in the cecum of rats receiving no dietary protease 80,81

Supplementation with -LA and LTA revealed superior ability to improve glucose tolerance test and skeletal muscle glucose uptake, reduce hyperinsulinemia, and enhance body composition by increasing lean mass relative to fat, compared to gene therapy or liver-targeted insulin administration

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