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Aluminum modifies the properties of Alzheimers disease PHF tau proteins in vivo and in vitro

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Contribution statement RM conducted the analyses, prepared tables and figures, interpreted the data and co-wrote the manuscript

In both assays, drug-treated extracellular Wolbachia were still viable, suggesting there is no direct killing action

4 Pathematology and pathogenesis 4.1 Pathematology of ARHL Studies on the morphology of the human temporal bone during life and after death have shown that ARHL is caused primarily by damage to cochlear sensory cilia, atrophy of the cochlear vascular stripe, thickening of the basilar membrane, damage to the spiral ligament, and degenerative lesions of the auditory nerve/spiral ganglion

However, no data are available on MUC5B + -derived organoids cultured without hormones or under conditions supplemented with E2 + PGR agonists + cAMP, thus limiting the ability to draw conclusions on the phenotype and hormone-responsiveness of the MUC5B + epithelial cells [16]