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The company's track record speaks for itself: JNJ-2113 in Phase III for psoriasis, and a pipeline spanning IL-17 antagonists, obesity treatments, and hepcidin mimetics

Esteva FJ, Hubbard-Lucey VM, Tang J, Pusztai L

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doi: 10.3389/fendo.2026.1767726 Received 15 December 2025 Revised 26 March 2026 Accepted 30 March 2026 Published 30 April 2026 Volume 17 - 2026 Edited by Sadiq Umar, University of Illinois Chicago, United States Reviewed by Gustavo Roberto Cointry, National University of Rosario, Argentina Jiale Chen, Chengdu University of Traditional Chinese Medicine, China Updates Copyright 2026 Gong, Ma, Wang, Zhang, Liu, Li and Dong

While this is not a side effect in the traditional sense, it's important to be aware that long-term use of high doses for skin-lightening purposes may have unintended consequences and may not be safe