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They include: Pain, redness, or swelling at the injection site Mild diarrhea or nausea Itching or skin irritation near the injection area A sensation of swelling throughout the body Headache or dizziness These effects typically resolve within 24 to 48 hours and do not require medical intervention

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K-means clustering analysis of amplicon sequence variants by animal demonstrated that NNMTi-treated DIO mice switched to LD had a distinct microbiome pattern that was highlighted by decreased Erysipelatoclostridium and increased Lactobacillus relative abundances compared to vehicle counterparts

Although a fairly large proportion of patients have reported a number of side effects, particularly at the gastrointestinal level (nausea, vomiting, diarrhoea), these side effects tend to diminish over time and adherence to treatment remains high, with about 5% of patients discontinuing treatment due to side effects

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