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Nitric oxide production pathways in erythrocytes and plasma

5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT)a metabolic regulator tied to fat storage, NAD depletion, and reduced energy expenditure

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References Substance Abuse and Mental Health Services Administration

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Taken together, these data suggest that CD11b + myeloid cells are the primary target of erucamide both in vivo and in vitro resulting in the secretion of pro-angiogenic and neurotrophic factors