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Transferrin, the major plasma iron-binding molecule, interacts with transferrin receptor protein 1 (TFR1) to deliver extracellular Fe 3+ into cells, leading to iron pool overload and increased cell susceptibility to ferroptosis [77]

In another study, it was found that inflammasome-mediated gut dysbiosis can cause hepatic steatosis in wild-type mice when cohoused with MASH-affected mice (117)

Inflammasome Activation and Function in Liver Disease

Major sites of ROS generation in the mitochondrial electron transport chain (ETC) are depicted

These fungal species are crucial for maintaining intestinal homeostasis and systemic immunity [12]

Si toma medicacin para la diabetes o para tratar el colesterol alto, consulte a su mdico tratante antes de tomar orlistat, pues la prdida de peso puede hacer con que sea necesario modificar la dosis de estos medicamentos