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GOT2 silencing also significantly inhibited cellular ATP production and cell proliferation, indicating suppression of mitochondrial respiration (109)

5 Hematology and Bone Marrow Transplantation Unit, Pisa, Italy Background: Autologous stem cell transplantation (ASCT) is currently approved as the gold standard first line treatment for multiple myeloma (MM) patients (pts) younger than 65 years, furthermore it is considered feasible in fit elderly pts in some retrospective studies