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Moreover, nano differential scanning fluorimetry (nanoDSF) demonstrated similar melting temperatures ( T m ) for both QMP (63.1 C) and QMP/LX (64.2 C), comparable to that of WT albumin (63.7 C), supporting that the thermal stability of QMP is unaffected by the absence of L585 (Table 2, Supplementary Fig

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Heterozygous individuals may still only develop clinically significant methemoglobinemia under oxidative stress, albeit with a lower threshold [8]

PS exposure, cell size, calcium levels were measured by flow cytometry, and hemolysis was measured by absorbance assay

Sampietro M, Lupica L, Perrero L, Comino A, Martinez di Montemuros F, Cappellini MD et al