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Enzymology of the carnitine biosynthesis pathway

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L-Carnitine as an ergogenic aid for patients with chronic obstructive pulmonary disease submitted to whole-body and respiratory muscle training programs

Linus Pauling Institute

Transport of long-chain fatty acids Carnitine facilitates transport of long-chain fatty acids from the cytosol compartment of the muscle fibre into the mitochondria, where they undergo -oxidation and produce acetyl-CoA, which enters the Krebs cycle [27]

Although, in the younger population, a number of studies could not show weight loss after intake of l-carnitine [89], in a recent meta-analysis, Pooyandjoo and colleagues came to the conclusion that body weight was significantly reduced in subjects who received l-carnitine compared with the control groups