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Because of their lower activation threshold at baseline 7 , MZB need mitochondrial GSH for their correct metabolic reprogramming and therefore Gclc -ablation leads to MZB loss

Neurosci Biobehav Rev 21:15166, PMID: 9062938 Stewart VC, Stone R, Gegg ME, Sharpe MA, Hurst RD, Clark JB, Heales SJ (2002) Preservation of extracellular glutathione by an astrocyte derived factor with properties comparable to extracellular superoxide dismutase

The improvement of ovarian function in PCOS mice by PLB was manifested at several levels

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Such endothelium protection creates conditions in which endothelial sprouting and maturation may occur

1996 Sep;35(9):669-74