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Clin Endocrinol Metab 13 : 113143 Juul A (2003) Serum levels of insulin-like growth factor I and its binding proteins in health and disease

While other cell lines such as osteoblasts or endothelial cells may also provide valuable insights, the use of L-929 cells ensures compliance with regulatory standards and allows direct comparison with prior studies in the field

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This pathway demonstrates lactates function as an active signaling agent in angiogenesis and underscores the therapeutic potential of targeting MCT1 for both metabolic inhibition and suppression of neovascularization [216]