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[24] [25] [26] It is these 22 compounds that combine to give a vast array of peptides and proteins assembled by ribosomes

The GHR belongs to the class 1 cytokine receptors which uses STAT as one of its principal secondary messengers, and the subsequent phosphorylation of two STAT5b molecules results in a phospo-STAT5b homodimer which translocate to the cell nucleus, binds to STAT5b recognition sites on the IGF1 gene promoter, and initiates transcription (Figure 3)

In the first set of experiments, 24 animals were used to monitor the survival rate during 12 days

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