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Additionally, the KRAS- and PAR4-associated proteins ERK and RhoA were examined to confirm that the effects of iMQT_020 were specifically mediated through the inhibition of SLC1A5_var but not off-target interactions (Supplementary Fig

Overload induced heat shock proteins (HSPs), MAPK and miRNA (miR-1 and miR133a) response in insulin-resistant skeletal muscle

The stop codons are UAA, UAG, and UGA

Kim WB, Chung HK, Park YJ, Park DJ, Tahara K, Kohn LD, et al

19,20 The immune system participates in the dynamic balance between organs through inflammatory responses and immune surveillance, 21,22,23 and the circulatory system provides the physical foundation for interorgan communication by delivering nutrients, oxygen, and chemical signals through blood flow

Two signaling cascades have been described as the master regulator for osteoblastogenesis, bone morphogenic (BMP)/SMAD signaling pathway and Wnt/-catenin pathway