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Furthermore, iron deficits have been specifically related to severe dopaminergic dysfunction in animal models, either by constraining systemic iron intake 21,22,23,65 or by suppressing neuronal iron uptake 24

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For a complete regulatory breakdown, see our TB-500 FDA Approval Status 2026 guide

342 Vitamin B deficiencies, particularly of B12 and B6, can exacerbate neurological dysfunction in DPN