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DOI: 10.1210/endrev/bnad019 Imai S & Guarente L (2014) Trends in Cell Biology , 24(8): 464471 (npj Aging) Foundational review confirming the intimate connection between NAD+ availability and sirtuin activity as a conserved ageing/longevity regulatory axis

doi:10.1016/S0026-0495(96)90171-7

3 The Schilling test also has fallen out of favor because it is complicated to perform, the radiolabeled vitamin B 12 is difficult to obtain, and interpretation of test results can be problematic in patients with renal insufficiency

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