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Nevertheless, several of these aspects have been successfully sorted out over recent years through the new technologies available in peptides design field: new bioinformatics tools in combination with other approaches such as virtual screening, structure-based drug design, high throughput screening (HTS) and chemical strategies, provide a comprehensive pharmacological description of putative peptides, improving their chemical and physical features (119, 121, 148)

Science 246 , 382385 (1989)

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With the advancement of omics technologies, mass spectrometry, and network pharmacology, the bioactive components of TCM and their molecular targets are being increasingly elucidated

Multi-center, randomized, placebo-controlled trials of epitalon, BPC-157, TB-500, and Semax in elderly populations could definitively establish efficacy and safety, potentially bringing these agents into mainstream gerontological practice (Wang et al., 2022)

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