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Moreover, the in vivo results demonstrated the ability of GliSODin to reduce differentiated Th2 and Th17 cell reactivation by reducing their proliferation, confirming previous studies showing that ROS upregulates costimulatory surface molecules CD40, CD86, and MHCII and promote T-cell proliferation (32)

ER is generally associated with promoting adipogenesis and reducing lipolysis, while ER tends to have anti-adipogenic and protective effects against excessive fat accumulation

10.1128/AEM.03153-20 26 RuJ.LiP.WangJ.ZhouW.LiB.HuangC.et al (2014)

Int J Food Microbiol 136(3):295303 Xu P, Qiao K, Stephanopoulos G (2017) Engineering oxidative stress defense pathways to build a robust lipid production platform in Yarrowia lipolytica

Thus, the inhibitors of histone deacetylation or demethylation may be promising agents for MS treatment