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The pleiotropic role of p53 in functional/dysfunctional neurons: Focus on pathogenesis and diagnosis of Alzheimers disease

Eur J Pharmacol 793:5665 Acknowledgements This research was supported by the Ministry of Science, Education and Sports, Republic of Croatia (Grant Number 108-1083570-3635)

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The evidence suggests that by changing the exosomal content and load, melatonin may potentially improve the nature of exosomes associated with diseases with recognized molecular background

Indeed, Soares and colleagues report that four hours after a single excess dose of APAP, adult mice brains exhibit mitochondrial dysfunction and oxidative stress 85

This pathway generates pentose sugar for synthesis of amino acid and nucleic acid and converts glucose to ribulose-5-phosphate via retrieving the carbon from the pentose phosphate shunt.78 Vitamin B2 (Riboflavin) plays an important role in many biologically important redox reactions such as energy producing, biosynthetic, detoxifying and electron scavenging pathways as a precursor of coenzyme flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) (9-10)