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The active form is commonly called GSH and the inactive form is called GSSG

Excretable hydrophilic metabolites are usually produced during phase II metabolism by glutathione S-transferases, uridine 5-diphospho (UDP)-glucuronosyltransferases, sulfotransferases, N-acetyltransferases, and epoxide hydrolases

When the autophagy flux is compromised, Nrf2 signaling is activated

24,25 Laboratory results showed that the counts and percentages of lymphocytes including CD4 + T, CD8 + cytotoxic T, 26,27 natural killer (NK), 24 and B cells 25 were all reduced in COVID-19 patients

Collectively, these approaches represent a new era of mitochondria-centered therapeutic innovation, offering the potential to complement traditional antimicrobial therapies and mitigate infection-induced tissue injury

Specifically, cannabinoids are substrates of the CYP enzyme family [165]