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Furthermore, IL-6 stimulates angiogenesis through the upregulation of VEGF, further supporting tumor growth and metastasis [133]

3 Overview of antioxidative and other molecular mechanisms through which Se influences male fertility As previously mentioned, certain amounts of oxidative stress and ROS are necessary for normal sperm maturation, motility, activation, and fertilizing ability (18, 94, 118, 141, 142)

[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Lee K.E., Khoi P.N., Xia Y., Park J.S., Joo Y.E., Kim K.K., Choi S.Y., Do Jung Y

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Oncogene 27 , 39443956 (2008)