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Results Synthesis and preparation of cysteine conjugates We synthesized the cysteine conjugates of APAP and PAP using organic synthesis according to the detailed description in the methodological part

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Class I FINs activate ferroptosis by depleting intracellular GSH by inhibiting system X c - [17, 95, 103, 104]

de SISPeronAPLeimannFVBressanGNKrumBNFachinettoRet al In vitro and in vivo evaluation of enzymatic and antioxidant activity, cytotoxicity and genotoxicity of curcumin-loaded solid dispersions

Overall, Shen Ze Shu Gan Caspulse exert a integrated effect on NAFLD, including oxidant stress, cell death, lipid metabolism, inflammation, fibrosis, gut dysbiosis, etc