mácula melanótica oral causas labial - Hoogstra Macula Melanótica: Definición, Causas y

In vitro models of the bloodcerebrospinal fluid barrier and their applications in the development and research of (neuro)pharmaceuticals

Persistent hyperglycemia, a hallmark of diabetes and insulin resistance, initiates the Maillard reaction, a non-enzymatic chemical process in which reducing sugars react with amino groups on proteins and lipids, resulting in the formation of AGEs (106)

BMJ 310 : 1534 Chard MD et al

So that means their immune system considers it to be a problem

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