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The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics

Stimulation of CD25 + CD4 + regulatory T cells through GITR breaks immunological self-tolerance

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However, under chronic antigenic conditions such as persistent viral infections and tumors, ACSS2 ablation significantly reduces the IFN- production in CD8 T cells, indicating a particular need for acetate in nutrient-restricted conditions [62]

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