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V., & Mjasoedov, N

These higher intakes of niacin also cause some side effects other than skin flush including nausea and, in rare cases, liver injury

Slow-wave sleep was not increased consistently

however, we note that stability, subcellular localization, transcriptional activity, and interactions among proteins and signaling pathways are also under circadian control (reviewed in Okamoto-Uchida et al., 2019)