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We also acknowledge that MAD itself may be proximal to other risk factors, especially diet, since the diet can greatly affect the oral and gut microbiomes, metabolic state and infection susceptibility (Santonocito et al., 2022

[DOI] [PMC free article] [PubMed] [Google Scholar] 63.Herreman L., Nommensen P., Pennings B., Laus M.C

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Lpez-Cano and colleagues conducted a double-blind, randomized, crossover, placebo-controlled clinical trial investigating the effects of liraglutide over a 7-week period, while minimizing weight loss as a confounding factor