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Dogs obtain B12 from their food, but for it to be used by the body, it must first be absorbed correctly through the small intestine

Bosn J Basic Med Sci 9(3):215220

The pore pathway has a high capacity for low-molecular-weight molecules, while the leak pathway allows the passage of high-molecular-weight molecules at a lower capacity [45]

& Dominiczak, A

10.1093/nar/gkq347 15

Centrally, it also influences dopaminergic and GABAergic neurotransmitter systems, which may contribute to its observed effects on stress-related tissue damage