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Various studies targeting ER stress signaling pathways and components of the UPR have demonstrated that CHAC1 expression is upregulated downstream of the ATF4-dependent signaling pathway (Figure 4)

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[DOI] [PubMed] [Google Scholar] 17.Morgenstern R., Zhang J., Johansson K

[DOI] [PubMed] [Google Scholar] Scheidegger KJ, James RW, Delafontaine P

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