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Hydroxocobalamin , on the other hand, does not function as a coenzyme, but scavenges toxins/free radicals

ASIC1a is a proton-gated Na + and Ca 2+ ion channel that can be activated in response to acidic pH (Yermolaieva et al., 2004), and it has been shown to participate in seizure termination by activating hippocampal inhibitory interneurons, which exhibited larger H+-gated densities than excitatory pyramidal neurons (Ziemann et al., 2008)