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R2 : How well do predictions from global models compare to observed values at locations not used in the map calibration/training, i.e., what is the expected prediction error at unvisited locations

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Furthermore, standard guidelines for adequate characterization of nanomedicine in physicochemical and biological evaluation are absent, which complicates the entry of nanomedicines into clinical trials (Gaspar et al., 2014

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These molecular alterations are currently under investigation as potential predictive biomarkers for therapeutic efficacy (102)