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Importantly, MS patients who showed a significant increase in the expression of NRF2s downstream target, NQO-1, following DMF treatment were more likely to achieve no evidence of disease activity after 1 year (Hammer et al., 2018)

Bright Curcumin and Curcuma longa Extract in the Treatment of 10 Types of Autoimmune Diseases: A Systematic Review and Meta-Analysis of 31 Randomized Controlled Trials by Zeng et al

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These improvements are usually gradual rather than dramatic

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HCMV infections usually progress subclinically in healthy adults, but cause morbidity and mortality in individuals with immature, impaired or senescent immunity, such as congenitally infected newborns, AIDS patients, transplant recipients and the elderly (Griffiths & Reeves, 2021)