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Mice were maintained under controlled conditions of humidity (50 10%), light (12/12 h light/dark cycle), temperature (23 2 C) and given free access to a standard NIH-31 chow-diet (1019018, Xietong Bio, Nanjing, China) and water ad libitum

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Mechanism 2: Growth Factor Upregulation BPC-157 stimulates multiple growth factors involved in tissue repair: FGF (Fibroblast Growth Factor) promotes fibroblast activity and collagen synthesis HGF (Hepatocyte Growth Factor) cell growth and tissue repair TGF- (Transforming Growth Factor Beta) tissue repair and regeneration These factors are literally the building blocks of collagen-rich connective tissue

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Comments submitted after July 9 but before the docket closes will still be considered by FDA