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Low GSH in aging is associated with lower intake of GSH precursors, mainly cysteine, and lower GSH synthesis evidencing diminished function of nuclear factor erythroid 2related factor 2 (Nrf2)-dependent inductive mechanisms that enhance glutamate cysteine ligase expression, rate limiting factor for the synthesis of GSH (McCarty and DiNicolantonio, 2015)

10.1016/j.redox.2024.103120 11 BodmerJ

Gut microbiota-targeted therapeutics for metabolic disorders: mechanistic insights into the synergy of probiotic-fermented herbal bioactives

Sci, 2020, 6, 207212

Ultimately, this network drives ovarian dysfunction and a range of clinical manifestations

Here we used the latter property to monitor the oxidative and reductive half-reaction