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Arginine is also indispensable for IL-2 signaling because arginase deprivation suppresses the expression of the IL-2 receptor [235, 236]

PMCID: PMC10220156

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In the central nervous system (CNS), inflammation is considered as a common mechanism in neurodegenerative diseases, characterized by activation of astrocytes and microglia in response to brain injury

Flippase is an enzyme active under basal conditions that shifts PS from the outer to the inner membrane leaflet, thereby preventing PS exposure