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But if left untreated, it may cause the following symptoms: Weakness, tiredness, or lightheadedness Lack of energy A decline in your mental abilities, such as memory and focus A painful and red tongue (glossitis) Mouth ulcers Pins and needles (paraesthesia) Disturbed vision Irritability Causes of Vitamin B12 deficiency

REDUCES DARK SPOTS: The skin-brightening effect of L-Glutathione, along with Vitamin Es antioxidant properties, helps to reduce the appearance of dark spots, hyperpigmentation, and blemishes

118 OTUB1 is overexpressed in a variety of human cancers, and it can inhibit ferroptosis by stabilizing SLC7A11

7 Conclusion and future perspectives This study reviewed the characteristics, isolation, purification, and biological activities of MEVs

The authors thank Prof Liwei An for manuscript editing and language polishing